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Why We Haven’t Cured Cancer

Why We Haven’t Cured Cancer


According to the American Cancer Society,
between one third and one half of the people in the United States will develop some form
of cancer in their lifetimes. So scientists, doctors, and the many organizations
that fund their research, are what you’d call “motivated” to find a cure. But… they haven’t found one, if you hadn’t
heard. Plenty of drugs and treatments have been tested,
but they often don’t seem to work. One person can take a cancer drug and get
better, but another person — with the same type of cancer — can take the same drug and
not get better. So, after billions of dollars and decades
of research, why haven’t we cured cancer? Well, a better question is why do we keep
talking about “THE cure for cancer”? If every tumor worked the same, we would probably
by now have that magic bullet that we need. The trouble is, cancers may look the same
on the outside, but each one develops differently in their own way, and can originate in any
type of tissue. So we haven’t found a cure for cancer, because
it’s not a single disease. If we’re going to beat them, we’re going
to have to take on all of the cancers, one at a time. So the challenges start with the basics here:
first we’ve got to figure out what cancer actually is. We tend to think of cancer as one thing because
we have one word for it. But the word “cancer” really refers to lots of different conditions
that have a few similarities. The main thing cancers have in common is uncontrolled
cell division. And that uncontrolled growth usually starts from a sudden change within
a small set of your genes. No matter what triggers it, you get the same
result: a mass of cells growing out of control and invading other tissues, which is very
bad for the body. But under the hood, each cancer works differently.
It’s practically a different disease every time, and not every cancer will progress in
the same order. Mostly, that’s because every cancer is caused
by a different set of genetic mutations. Genes consist of a sequence of DNA, and each
sequence is a set of chemical bases called nucleotides that are arranged in a very specific
order. Together, they tell the cell how to manufacture proteins, and we are mostly just
made up of proteins – so that’s how we build ourselves. Mutations change those instructions, and that’s
where things start to go wrong. Now, we know by this point that cancers usually
come from mutations of two kinds of genes, called oncogenes and tumor suppressors. An oncogene starts out as just a normal gene
that codes for proteins that signal the cell to grow. And normally, they just spend a lot of their
time dormant, because growth is generally good, but cells shouldn’t always be growing. But just one mutation in one of these genes
is often enough to throw it into high gear, and it can’t be turned off. That’s when it becomes an oncogene, telling
the cell to keep growing and dividing over and over, even when it shouldn’t. That’s
also when it gets dangerous. Some of the most well-known oncogenes — the
usual suspects, if you will — are RAS and MYC. They’re especially powerful growth
genes that show up in many kinds of cancer. A lot of the time, it’s the RAS gene that
somehow gets mutated, which changes the shape of the protein that it makes. The altered
protein gets stuck in a position that always sends a signal for the cell to grow, whether
it’s supposed to or not. And with its new shape, other proteins — ones
that usually deactivate the RAS protein before things can get out of hand — can’t recognize
what they’re supposed to be targeting and switch it off. So the cell never stops getting the signal
to grow and divide, and it starts forming a tumor. Then there are tumor suppressors, another
type of cancer-causing gene — and they’re actually the opposite of oncogenes. As you might guess from their name, tumor
suppressors stop a cell from growing, unless conditions are just right. As with all of your genes, every cell in your
body has two copies of the tumor suppressor, so they’re harder to put out of commission:
Even when one copy is mutated, the other one still works. But of course, cancer has a tendency to find
its way around all kinds of safeguards. Often, a tumor suppressor might be mutated
on one chromosome to the point of not working at all. Then, the cell just happens to lose
the chunk of DNA containing the other copy. With one copy mutated and the other deleted,
there’s no tumor suppressor left to restrain the cell’s growth. And those mutations can happen in any number
of ways. With so many possible combinations, we can’t just create a drug to keep tumor
suppressors from mutating. Which is where things start to get even more
complicated. Because just one mutated gene isn’t usually enough to cause cancer — it
really takes at least five or six genetic changes before normal human cells become truly
cancerous. Then, as tumors get bigger, more and more
genes tend to mutate. Some of those mutations make the cancer nastier and more aggressive. How quickly this happens varies a lot, with
different rates being associated with certain kinds of cancer. But there can be thousands of possible combinations
of mutations going on in a cell — which is partly why a drug might not work for some
patients, even if it’s proven effective for that type of cancer. So every single tumor will follow a different
genetic path, which makes it hard for doctors and drug-makers to know what to target. So how do you kill a tumor cell, when you
don’t know which of the potentially dozens of problematic genes are making it grow? The most obvious way to treat a tumor is to
get a knife and cut it out of the body. That’s called resecting it. But it’s not always
possible, and even when it is, sometimes they grow back. So typically, you go to Plan B: Use a blunt
instrument to smash the cancer, and hope for the best. For a long time, the best cancer therapy we’ve
had is to send in a treatment so toxic it attacks all rapidly dividing cells in the
human body, instead of just the cancer. Those treatments are chemotherapy and radiation. The kind of radiation that’s useful in cancer
treatment is ionizing radiation — the kind whose energy can ionize atoms, and the kind
that most people mean when they talk about “radiation.” And it works simply because
it can tear DNA to shreds. Once the cancer cell’s DNA is mangled beyond recognition,
it can no longer make copies and divide. But of course, it damages the DNA of nearby,
healthy cells too. So doctors try to aim it right at the tumor, to expose as little healthy
tissue to the radiation as possible. And then there’s the group of drugs we refer
to collectively as chemotherapy. These drugs work in a few different ways,
but because they circulate through the bloodstream, they tend to affect the whole body. Some types of chemo imitate one of the building
blocks of DNA, so that cells try to incorporate them into their chromosomes without realizing
they’re useless. Other kinds target the cell’s cytoskeleton — its internal framework
— so that it can’t pull itself apart when it divides. These kinds of chemo can stop a cancer cell
from dividing — but again, there are a lot of healthy cells in your body that need to
divide, as well. Hair follicles need to go on producing hair,
and the lining of your gut needs to constantly renew itself against harsh stomach acids.
That’s why chemo causes hair loss and digestive symptoms, along with a whole bunch of other
nasty side effects. It can work, but it isn’t pretty. Fortunately, there are new alternatives. One of the newest weapons in the battle against
cancer is one that biologists have been refining for decades: Genome sequencing. It’s faster and cheaper than anyone dreamed
possible even ten years ago, and it’s finally ready to directly help patients. Within a matter of days, scientists can now
sequence lots of different types of cancer cells, and figure out exactly where and how
their genes were mutated. Using that information, they can predict what
drugs will be effective against those cancers. So, instead of using a blunt instrument that
kills pretty much everything it touches, we can develop much more refined ways to treat
a certain cancer, in a certain person, through personalized medicine. Two major projects have taken the lead on
this new approach — one’s called the Cancer Genome Project and the other, the Cancer Cell
Line Encyclopedia. They’ve tested many kinds of cancer cells and drugs on a large scale. In both cases, researchers confirmed that
certain drugs are more effective against particular types of cancer. Some drugs, for instance,
work better for brain cancer than stomach cancer. They also found that they could predict the
effectiveness of a drug based on the mutations that they find in a particular set of cancer
cells. So choosing drugs for cancer treatment doesn’t
have to be a shot in the dark anymore — at least, in theory. There’s a serious problem, though. One study compared the results of the Cancer
Genome Project and the Cancer Cell Line Encyclopedia, and it found that they came to different conclusions
alarmingly often. When the two different groups of researchers
treated the same cancer cells with the same drugs in a lab, they got different results. Even though the cells they used were more
or less identical, they would sometimes respond differently to the exact same drugs. And even when the two projects agreed that
a drug could treat a certain kind of cancer, they disagreed about what dose was needed
to be effective. So, we won’t be able to count on personalized
medicine to work until scientists come up with more effective ways to test these drugs,
and figure out how to use them in people. So there are still some glitches to work out,
but it’s probably the most promising lead we have in the fight against cancer. So it’s true: We haven’t found one cure
for cancer yet, but that’s kind of a question wrongly asked; there is no cancer to cure
— there are lots of cancers we need to cure. Advances in things like DNA sequencing mean
that, even though there are as many cancers as there are cancer patients, soon there may
be as many cancer treatments as there are cancers. And that’s pretty good news. Thank you for watching this scishow infusion;
I hope it was educational for you. It was made possible by our patrons on Patreon. If
you want to help us keep making videos like this, check out patreon.com/scishow. And don’t
forget to go to youtube.com/scishow and subscribe for more.

100 thoughts on “Why We Haven’t Cured Cancer

  1. Here's why we haven't cured cancer: There is more money to be made in treating the symptoms of a disease than there is curing it. This is the type of result you'll get, EVERY TIME, with an unchecked corporate mentality.

    Furthermore, it's WAY PAST time we insist that the Government breaks up the thinly veiled monopolies (Cough Cough, Wal-Mart) and also regulate legitimate corporations MUCH MORE FIERCELY.

    The American dream has become American indentured servitude. You better pucker-up those butt-cheeks. I'm extensively educated in a wide range of different fields, and nevertheless Corporate America has chewed me up, and spit me out, THREE TIMES ALREADY. I'm only 38.

    Although I'm ashamed to admit this, we have allowed corporate-greed and their lobbyist whores to mold our society into something utterly disgusting.

  2. Because the government is too greedy to give us the cure they already know. How many presidents have died of cancer? 😒

  3. First of all we dont cure anything (not just cancer), we just deal with the symptoms of the diseases. 2nd why would we seek a cure, there is no money in that!

  4. https://youtu.be/OBm2NSMeMhk

    Cure for cancer Antineoplastons basically peptides and amino acids in urine and blood that cancer sufferers do not have in their bodies. So..take in these antineoplastons and cancer growth halts and reverses. Problem solved. No more cancer.

  5. Stress…bad energy…and foods that not even my dog wants…is the cause of this nasty disease….the answer to all of you is this …call me idiot or whatever…….garlic….and music…it has working for me ….l m not going to tell you how to use garlic…is my secret

  6. Motivated to find a cure?? You must be joking! Why would the pharmaceutical industry want to lose the billions they make on all the useless treatments they offer?

  7. Here's an unpopular opinion, I personally think trying to cure cancer is wrong and we should stop, you see millions of mice and rats are being killed by cancer research and it's just not fair, personally I think animals are better than people, there simple creatures and more importantly they are pure, they do what they must but are never perilously mean or cruel, they dont do stupid things, or try to impress there freinds, they dont bully nerdy animals or act greedy or bratty, humans are often cruel and needlessly hurtful to others, and yet we kill millions of these beautiful creatures in the hopes that we might save some evil human scum, I know not all people are evil, but no animals are evil, why are we so damn selfish, I saw some leaked pictures from the Jackson lab in maine, labrats were having there tails amputated and other painful
    Things for research purposes without using anesthetic, all the while, cancer is a natural thing that exists in nature, if it didn't have negative effects than I'd be down, but the negative really outlays the positive with the cancer cure, dont get me wrong, If it was discovered id be very happy, but its hasn't been, and rats are still dying, so i want it to stop.

  8. There's cures out to do the job but, the big Pharms are not going to let it happen simply because, if it's cured they won't make anymore money on that person. It goes on and on. It's all about money, money, money.

  9. At school i got told Killing cancer is easy BUT killing cancer with out killing the human is HARD….. the HOLY GRAIL is to target cancer & only Cancer Once that is done we wont kill healthy cells that mutate rapid like hair & stomach thus killing the human.. if a method to just target cancer was found then some 1 already had idea to bind the cells to prevent further mutation CANCER SPREAD STOPPED SIMPLE…. But to think that a cancer patient that been told he got weeks to live can catch a infection from a mosiquito bite & some how totaly cure him self from cancer & the other infection all A O K this has hapend multiple times lending support to the body will sort cancer it self if only its immune system knew about it. & either way HOW MANY YEARS OF RESEARCH & WE NO FURTHER FORWARD PLEASE GIVE UP….. CHECK THE BIOCHEMIST THAT GOT SACKED FROM CANCER RESEARCH FOR NOT BEING QUALIFIED & STILL GOT £85,000 PAID FOR 3 MONTHS SICK PAY SHE WORKED FOR THEM 10 YEARS…………….PLEASE PAY THEM ON PERFORMANCE

  10. Cancer develops in cells with a bad metabolism. Typically in cells with a low pH and inflammation. Cells with a normal metabolism do not get cancer. Abnormal cell metabolism is always due to deficiency or toxicity. Cure the cause and not the cancer. Depending on the stage of cancer and state of organs and immune system most cancers can be cured treating the cause.

  11. we have cured cancer, but the FDA shut it down because they want a profit $$
    Look up Dr Burzynski's cancer documentary on you-tube – while it's still up

  12. There is a cure but big pharma wont let it be sold or used! Itll take away from their billions of dollars treating it! A patient cured is a customer lost! Like I said they make way to much money treating it rather than curing it! Even if they allowed it to be sold it would cost an outrageous amount of money because they are corrupt and greedy!

  13. Please.
    To cure it would close down the oncology industry. Cancer makes doctors rich. Only a fool cuts off the hand that feeds him. Welcome to the real world. Sorry.

  14. Cancer is cured but the pharmaceutical mafia are using the illegal legal system to prevent it getting into the Main Stream but it’s coming. I promise it’s coming. By the way it’s called GcMAF. It cures almost all tumours more than 90%. The measles’s virus works at shrinking tumours and there is much more products simple and cheep. Don’t listen to this bull shiter.

  15. Cancer is in our DNA people we don’t have proper DNA splicing technology to get it out of people’s genes

  16. David Noakes and Lyn Thyer are sitting in prison for manufacturing a cure for cancer.
    Gc Maf, Globulin component Macrophage Activating Factor is a product made from human blood, sold by Guernsey based company called Immuno Biotech.
    Big Pharma have had them both arrested. Lyn Thyer has been extradited to France. She is very ill and also needs to care for her sick mother, instead she's sitting in a French jail waiting for the next two years for her trial to come to court. She's facing up to 15 years in prison, for curing people of terminal cancer.

  17. Population control. If you don't think there is a cure for cancers your not thinking. The best we can do unless someone with ethics comes forward is have a low acidic high alkaline diet.

  18. Mr. Burzynski
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    Copy and Paste!!!!!!!!

  19. THIS GUY
    must Be a FDA PAWN! Talking about incurable.. brain cancer / Colon Cancer / No chance Cancer!.. Have Been cured during 1990's ERA!!

  20. It would cost the Cancer "Industry" too much money…they don't want to cure it, but non medical cures for cancer already EXIST and have for a long time…this video is crap!!!

  21. It would cripple the GNP to find cures for cancer as the medical profession makes billions on researching and “treating” cancer. The real question is…why are natural cancer treatments and those who provide them suppressed or banned in the USA? Natural treatments have a far higher cure rate than the usual cut, burn and poison methods…but the money is what it’s all about…not one’s health.

  22. It's really annoying if 95% of what you see is the person that's teaching instead of seeing what's being taught. It doesn't help either if the same script is just being flashed from time to time.

  23. Yeah right, like we haven't progressed hardly one bit in cancer treatment in the last 50 years! But everything else in the world progresses … Nonsense.
    Do some research. Cancer has been cured many times. When people have found cures the medical community has shut them down. Too much money involved in keeping things the same! So you have to go to Germany or Mexico for treatment.
    Of course you can could just stop eating meat and dairy. Look it up.
    Meat and dairy are the cause of most of today's cancers. Stop eating them and you'll not get cancer. And you'll have more energy too.

    Check out this video:
    https://www.youtube.com/watch?v=Og62hbNl794

  24. We haven't found a cure because there's too much money to be made! Ho many millions ps does the national cancer association currently get ………The cure is in the Cause…..too may toxins not enough Nutrition.

  25. Coz its a 170 billion dollar business, melbourne in australia announced cure for cancer will be released in forty years ill be 84 yrs old .

  26. because it is such a huge business that if we find a cure, the business won't do so well anymore (no need for repeated sessions of treatment)

  27. It is so complicated, seems almost impossible to find the right cure for each type of cancer, unless we get down to genomic level and fix ourselves from there…

  28. Big Pharma prohibits cures unless they can get a patient. Check out Germany. They have many alternate cancer treatments that work.President Reagan received the High temprature treatment for colorectal cancer in Germany. I went with the insulin potentiated therapy when i was diagnosed with prostate cancer. That was in 2011. Blood tests every year has shown that i am ok. Go to Cancertutor.com for great info. By the way, it was in Reno Nevada that put me on to the ipt treatment. Get Suzanne Somer's book " Knock Out". That's where i got the info.

  29. Doctors & medical scientists are a joke. They raise trillions of dollars to this date to cure Cancer, AIDS, etc and still make baby steps. They can’t even cure something as simple as hair loss. The money donating is a scheme

  30. Cancer might be cured but nobody is going to get it because the government will lose billions of dollars/euros. It makes me sick the governments are willing to give up millions of people dying for a peice of paper.

  31. Lots of cancers is made by our own Society feeding cattle steroids in chicken steroids and all sorts of other stuff that we shouldn't be giving our food cuz we got to eat it

  32. Oh yeah and you're leaving out marijuana CBD oil makes cancer cells stop multiplying in what happens when they stop multiplying means the cancer dies so don't forget about CBD oil in your videos

  33. We have always had cures. They’re not prescriptions. CancerTutor.com
    Naturopathic.org

    Also…the naturopathic doctors are replacing the medical doctors.

  34. Avoid eating so much rubbish and prevent it. Wondering when people started getting all these illnesses… when they introduced sugar? grains? when they told us to substitute all the good fats for tons of industrialized carbs?

  35. Let me guess because you can't stop the cells from dividing not to mention you can't kill the cells without killing the patient the cancer cell has everything it needs to survive, proteins, fats, acids and the heart to pump the cells to different parts of the body.

  36. We have a cure, it's not as complex as buddy makes it out to be but… There's more profit in suffering so why cure it when you can make bak treating symptoms? Such as radiation and Chemo which are horrific, to whom ever decided those were a good way of attacking cancerous cells… You need to be tortures for years to come. What a horrific legal experiment to subject a person to.

  37. Recently the extract cells from a certain type of snail prevents the growth of cancer cells. Still on clinical trial though. They are testing it for different types of cancers like breast and colon cancer.

  38. What if the way your body heals itself is in a way how cancer starts growing except the process becomes flawed. Through all the different genes of course.

    I like the genome process, it's more personalized for that type of cancer.

  39. Diet & lifestyle cause metabolic errors. Correction of diet & lifestyle will normalize the errors. There is much info on this all over the place, but hardly anyone is looking for something so simple. Big Problem is that the masses think that M.D. stands for Medical Deity, and they daren't trust their own judgment.

  40. Chew carefully raw vegetables, whole grain to secrete more enzymes and eliminate acid from our cells. That’s the key to alkaline body and wake up protect gene also cytokine system work efectively. should not eat animal because it make acid enviroment and cytotoxic. You can find the macrobiotic diet from professor Oshawa or Dr. Shinya for more information.

  41. We probably have the cure for cancer by now but big Pharmaceutical companies DONT want you cured.
    The longer you are sick the more treatments and drugs you will use.
    Pharmaceutical Companies: 💰💰💰💰😄 "Cha-Ching"

  42. Just letting everyone know if you change the search parameters to the time frames you can search any conspiracy videos from flat earth to John F. Kennedy

  43. First it might not ever even really be possible to cure cancer but even if they could they wouldn't too many charities too many doctors too many scientists too many pharmaceutical companies would be affected financially there's more money in the treatment than the Cure look at all the money that's drummed up every year just for cancer research through charitable organizations like Race for the Cure and yeah they call them non for profit organizations but you start looking into what some of these leaders of these organizations pay themselves and they most definitely are making a profit for themselves

  44. DreamLab is an app scientists have configured to simulate protein folding and cancer genetics and they are making groundbreaking discoveries with it, its open source distributed computing network as a weapon to solve cancer.
    donate idle cpu and help us finish the projects?

  45. they told my mom she had 2 months to live, but she went on for 2 years and got cured of 4 cancers, and then bone cancer, liver cancer, and breast cancer eventually…………..got to her

  46. its cus we are not letting Dr. Burzynski do what is needed,pretty sad if you do not know what i'm talking about just search cancer cure cover up.

  47. Just thought that another problem in sequencing is extraction of the DNA, as it will be different for every cancer cell you were able to sample, especially if another becomes more mutated than the other (even if it is in the same patient) 🙁

  48. my only problem with this kind of video is: why do you talk too fast? i'm literally grasping what you mean that I need to rewind… ah…that's the point….i get it. i will thumbs up your video everytime, if permited. thanks.

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